Submissions must be You (and co-authors) do not need to fill out forms or check disclosures as author forms are still valid If you are responding to a comment that was written about an article you originally authored: Your co-authors must send a completed Publishing Agreement Form to Neurology Staff (not necessary for the lead/corresponding author as the form below will suffice) before you upload your comment. You must have updated your disclosures within six months: If you are uploading a letter concerning an article: Thus, there are substantial obstacles to the use of MRI as a front-line tool in evaluating peripheral nerve.ĭespite these difficulties, notable successes are well documented, even in the anatomically complex brachial and lumbar plexi, where MRI is effective in characterizing neural involvement due to neoplasm and trauma. Moreover, because most peripheral nerve disorders do not cause nerve enlargement, this useful radiologic sign of disease is not relevant. 2 Nonetheless, MRI definition of even healthy nerves remains difficult. Also, on many sequences nerve is nearly isointense with muscle, prompting tailoring of pulse sequences to create MR “neurograms.” 1 These enhancements, including three-dimensional projections and diffusion weighting, were employed in early applications but are not included in more recent studies, in which improved imaging coils, high-field magnets, and fat saturation are used.

Nerves are close to blood vessels in key regions such as the brachial plexus, where on MRI they resemble vessels and can be obscured by flow artifact. Peripheral nerves are small and complex, challenging the best of MRI sequences.

In contrast with CNS disorders, MRI has had little impact on peripheral nerve disease.

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